top biotech venture capital firms 2021top biotech venture capital firms 2021

US biotechs still led on investments, although Europe Boston Cambridge Massachusetts Consistently, the top state for biotechnology industries in Massachusetts, particularly in the Greater Boston area. In 2022, over $14 billion was funded in Biopharma setup globally, and 37 major IPOs of VC-backed Biotech businesses raised a combined $4.2 billion. Possessing a diverse portfolio, this venture capital company has even invested in regenerative medicine and gene editing technologies. The capital total is a staggering 46% increase from its last set of funds, closed in May 2021 at $1.3 billion. The firm seeks to invest in seed-stage, early-stage, and later-stage companies. The Legal 500; Europe, Middle East & Africa . Venture capital financing, Private equity, The Best Original Streaming Shows Of The Last Few Years. The curated list of the most valuable private companies in the world |. OrbiMed invests across the global healthcare sector, from early-stage venture capital to sizable publicly-listed enterprises. Both of the companies DCVC held shares in that went public this year Recursion Pharmaceuticals and Zymergen were investments from DCVC's Deep Tech funds, a spokesperson said. WebThe 45 most important VCs in Texas, according to other VCs. (3)(2), Current biopharma portfolio companies: Calithera Biosciences, Catalyst Biosciences, Elcelyx Therapeutics, Galleon Pharmaceuticals, GlobeImmune, Mosaic Biosciences, NaZura, OncoMed Pharmaceuticals, Orexigen, Principia Biopharma, Promedior Pharmaceuticals, Ra Pharmaceuticals, Replidyne, Ribozyme Pharmaceuticals, Scioderm, Stemgent, Threshold Pharmaceutical, Tragara Pharmaceuticals, Trellis Bioscience, Vical, #14 (tie). The firm seeks to make minority investments in seed-stage, early-stage, and later-stage companies. Accel is a venture capital firm that concentrates on the following technology sectors: Consumer, Infrastructure, Media, Mobile, SaaS, Security, Customer care services, Enterprise software, and E-commerce. Synthetic biology investment set a nearly $8 billion record The firm and its SPAC partner, General Catalyst, have until March 2023 to find a company to acquire or return the money to investors. Medtech. New startups with unique concepts are developing as the Global Biopharma and MedTech Industries experience unprecedented growth. Founded in 2009, Capital Factory is a venture capital firm and an accelerator based in Austin, Texas. The firm invests in digital technologies across energy, infrastructure, and climate industries. Novo Holdings is the massive corporate investment arm of the Novo Nordisk Foundation, which is a majority shareholder in the Danish drugmaking giant Novo Nordisk. GEN Genetic Engineering and Biotechnology News, Molecular Structure Analysis and Quantification Tool Introduced for At-Line Biomanufacturing, Nanoparticles Rapidly Crystallize Proteins, Speed Up Purification, Alzheimers Model Mice Treated Using Targeted Protein Degradation, Digital Twins Illuminate a Path to Personalized Inflammatory Disease Treatment, Research Institute Focuses on Continuous Manufacturing of Advanced Therapies, Cell Therapy Sector Addresses Issue of Production Technology as Stumbling Block, http://blogs.wsj.com/venturecapital/2014/04/04/refocused-mohr-davidow-ventures-is-raising-a-new-fund/, http://finance.yahoo.com/news/lightstone-ventures-closes-first-fund-123257593.html, http://www.sec.gov/Archives/edgar/data/1612343/000161234314000001/xslFormDX01/primary_doc.xml, https://www.sec.gov/Archives/edgar/data/1602264/000160226414000001/xslFormDX01/primary_doc.xml, http://www.sec.gov/Archives/edgar/data/1609495/000160949214000002/xslFormDX01/primary_doc.xml, http://fortune.com/2014/10/02/exclusive-atlas-venture-is-splitting-up/, http://myemail.constantcontact.com/Announcing-Fund-VII.html?soid=1106633098844&aid=84wvr4fxTTs, http://www.sec.gov/Archives/edgar/data/1624149/000162414914000001/xslFormDX01/primary_doc.xml, http://www.sec.gov/Archives/edgar/data/1611731/000161173114000001/xslFormDX01/primary_doc.xml, Literature Review: Real Easy Real-Time Testing For Circulating Drugs. The firm prefers to invest in the direct-to-consumer, food and beverage, health and beauty, sports and fitness, apparel and accessories, accessible luxury, wellness, LOHAS, aging population, sustainable products, demand for personalization, humanization of pets, omnichannel, fem tech, and end of life sectors. Some VCs bet on a range of startups, like RA Capital, which had significant stakes in 18 companies that went public in 2021. While waning public investor sentiment made the year a minor disaster for listed companies, closely held groups enjoyed their most successful 12 months ever, with secured venture capital eclipsing 2020s then record-breaking total by 26%. The center of it all is biotechnology, with over 430 biotech companies. WebJan 9, 2023 08:00am. The entire Sprout healthcare technology team broke out into NLV in 2005. Amidst rising interest rates and the looming threat of recession, the once-hot IPO market has come to a grinding halt. 9 See announcement on the firms blog, http://indexventures.com/news-room/blog/our-new-fund-for-building-iconic-businesses Additionally, Bain Capital Crypto closed a $500 million fund in 3. To learn more about these VC firms and their 2021 investments take a look at their Crunchbase profiles: RA Capital Management OrbiMed Northpond Ventures Temasek City (cities) where offices are located: San Francisco, Fund size and status: $2 billion under management across eight funds, Current fund: $500 million Alta Partners VIII, a first stage-independent life sciences fund closed 2006, Current biopharma portfolio companies: 7TM Pharma, Ablynx, AcelRx Pharmaceuticals, Achaogen, Aegerion Pharmaceuticals, Aerie Pharmaceuticals, Aerovance, Alba Therapeutics, Allakos, Applied Genetic Technologies, Astex Pharmaceuticals, aTyr Pharma, Azelon Pharmaceuticals, Cara Therapeutics, Ceregene, Cerenis Therapeutics, ChemoCentryx, Chimerix, Corcept Therapeutics, CymaBay Therapeutics, Cytokinetics, DiscoveRx, Esperion Therapeutics, Excaliard Pharmaceuticals, Genedata, Immune Design, Intarcia Therapeutics, Kiadis Pharma, Kite Pharma, Lumena Pharmaceuticals, MacroGenics, Neothetics, Nereus Pharmaceuticals, Pathwork Diagnostics, Portola Pharmaceuticals, Proacta Therapeutics, Prolacta Bioscience, SARcode Bioscience, Scynexis, Silence Therapeutics, Sonexa Therapeutics, Sunesis Pharmaceuticals, Sutro Biopharma, Threshold Pharmaceuticals, Trevena, Veloxis Pharmaceuticals, ViroBay, VitrOmics, Zafgen, ZS Pharma, City (cities) where offices are located: Radford, VA; San Francisco; Palm Beach, FL, Fund size and status: More than $2 billion under management through nine affiliated investment funds, consisting of seven New River Management Funds and two regional funds, Current New River Management Funds: $120 million New River Management VII, closed 2012; $15 million Valleys Ventures, launched 2013 to invest in companies that intend to commence operations in, or are willing to relocate to an area within 100 miles of Montgomery, Roanoke or Botetourt counties of southwestern Virginia, Current biopharma portfolio companies: Agilis, AmpliPhi Biosciences, AveXis, Fibrocell Science, Halozyme Therapeutics, Intrexon, Oragenics, OvaScience, Soligenix, Synthetic Biologics, City (cities) where offices are located: Menlo Park, CA, Fund size and status: More than $2 billion under management in nine funds, Most recent fund: $670 million MDV IX fund, first closed 2007 at $580 million. WebAs of 2021, Venture capital-backed companies account for 62% of US public companies R&D spending! Boston-based. Angel (individual), Early Stage VC, Later Stage VC, Seed Round, Managing Director of Fund I and II and Fund I Deal Committee Member Rob Tucci. Largest investment: 9.1 million shares of Evotec worth $480 million at the time of its IPO, Total holding value of 2021 IPOs: $480.4 million. All non-U.S. currencies were converted into U.S. dollars on November 2124. Alta Partners. Technology and healthcare are two areas in which California-based New Enterprise Associates, Inc invests. Crunchbase Pro queries listed for this article. Boston-based RA Capital Management and New York-based OrbiMed ranked first and second, respectively, on the two lists compiled using Crunchbase data. Early Stage VC, Later Stage VC, Seed Round. While health and biotech are often almost inextricably linked, its worth noting that of that investment, a significant portion is heading directly to companies that place themselves specifically in the biotechnology category. The firm focuses to invest in business technology, digital experiences, and healthcare technology sectors. , however, participated in Adagios Series A, B and C rounds. The ecosystem of Biotech ventures peaked in 2021. See: http://www.sec.gov/Archives/edgar/data/1624149/000162414914000001/xslFormDX01/primary_doc.xml Flagship CEO Noubar Afeyan previously told Insider about the four-step creation process behind the firm's companies. Biotech Venture Capital Firms: Top Venture Capital Firms. Fund size and status: More than $14 billion in committed capital across 14 funds, Current fund: $2.6 billion New Enterprise Associates 14 L.P., closed 2012, Current biopharma portfolio companies: 3-V Biosciences, Acadia Pharmaceuticals, Adaptimmune, Alimera Sciences, Amicus Therapeutics, Ardelyx, Blend Therapeutics, BrainCells, Cadence Pharmaceuticals, Cardioxyl Pharmaceuticals, Cerecor, Cleave Biosciences, Clovis Oncology, Cydan, Dermira, Edimer Pharmaceuticals, Envisia Therapeutics, Epizyme, Galera Therapeutics, Glycomimetics, Hydra Biosciences, Hyperion Therapeutics, Intarcia Therapeutics, Intrinsic Therapeutics, Liquidia Technologies, Loxo Oncology, Lumos Pharma, Mersana Therapeutics, Mirna Therapeutics, Nexchem, NexImmune, Novast Holdings, Predictive Biosciences, Prosensa, Proteostasis Therapeutics, Psyadon Pharmaceuticals, Ra Pharma, Rhythm Pharmaceuticals, Rigel Pharmaceuticals, Roka Bioscience, Satori Pharmaceuticals, Sunesis Pharmaceuticals, Supernus Pharmaceuticals, Targacept, Tesaro, Transcept Pharmaceuticals, Tracon Pharmaceuticals, Trevena, Zyngenia, 1 The firm was ending investments in life sciences, and raising a fund in the $200 million range, according to an April 4 news report in Venture Capital Dispatch, a blog of The Wall Street Journal, in which the firm declined comment. Here is a list of the most active most active bio-tech, pharma and life science investors. Largest investment: 34.2 million shares of Sana Biotechnology worth $856 million at the time of its IPO. The German pharma giant Bayer's VC arm has made high-profile investments in health companies, three of which went public in 2021: Century Therapeutics, Pyxis Oncology, and Recursion Pharmaceuticals. Mubadala is a sovereign wealth fund, investing on behalf of the United Arab Emirates and the government of Abu Dhabi. Apeiron, Christian Angermayer's investment firm, is based in Malta and has $3.5 billion in assets under management. The largest deal of 2021 was the transaction of Treeline Biosciences (USD 735m), while the most active investor was Alexandria Venture Investments with 51 investments in 2021. The firm seeks to invest in the computer hardware, software, commercial services, and healthcare sectors. Foresite, based in San Francisco, is a healthcare investor that does everything from incubating startups to acting as a crossover investor in companies about to go public. WebAs of 2021, Venture capital-backed companies account for 62% of US public companies R&D spending! These startups and companies are taking a variety of approaches to innovating the Venture Capital industry, but are all exceptional companies See: http://finance.yahoo.com/news/lightstone-ventures-closes-first-fund-123257593.html Among RA Capital and OrbiMeds big bets this year was. Boost Heroes It has a variety of technologies spanning Biopharma, engineering, food, and other areas. This analysis didn't track how each VC managed their position after the IPO, such as buying or selling shares. Application Software, Automation/Workflow Software, Business/Productivity Software, Communication Software, Communications and Networking, Database Software, Entertainment Software, Financial Software, Internet Software, Media and Information Services (B2B), Multimedia and Design Software, Network Management Software, Other Information Technology, Software Development Applications, Vertical Market Software, Managing Directors Dan Watkins, Blair Garrou, Adrian Fortino, and Heath Butler. Two large investments in the synthetic-bio specialist Zymergen and the AI-focused drug discoverer Exscientia made SoftBank one of biotech's top investors of 2021. Samantha Stokes , Stephanie Palazzolo , Madeline Renbarger , Darius Rafieyan, and Ben Bergman. Despite the venture boom, fundraising by new niche VCs in America has fallen from a peak of $14bn in 2018 to an expected $5.5bn in 2021. As a spin-off of the Sprout Group, NLVP has been participating in Biopharma since 2005. The Legal 500 > Europe, Middle East & Africa > France > Private equity: venture/growth capital. Vivo is based in Palo Alto, California, but also has offices in Beijing, Shanghai, Hong Kong, and Taiwan. Over $14 billion was invested in Biopharma startups globally in 2022, with 37 notable IPOs of VC-backed Biotech enterprises raising a total of $4.2 billion. Largest investment: 13.6 million shares of Recursion Pharmaceuticals worth $245.1 million at the time of its IPO, Total holding value of 2021 IPOs: $473.5 million. The firm primarily prefers to invest in the information technology sectors. DCVC, based in Palo Alto, California, invests in what it considers "deep tech," so many of the biotech companies it gets involved with are focused on sequencing, artificial intelligence, and other data-driven approaches to healthcare. It's a great way to keep an eye on up-and-coming companies with The mean amount raised per round reached $84.4m in the first quarter, more than double that seen in the same period in 2020, while the median more than tripled. The firm seeks to invest in the business products and services sectors. WebAs of 2021, Venture capital-backed companies account for 62% of US public companies R&D spending! As per Forbes, Biopharma mergers generated a further $37 billion. The companys life science and healthcare investment portfolio spans the Biopharmaceutical, Biotechnology, medical equipment, services, and information and technology industries. With the unprecedented growth in the global Biopharma and MedTech industries, new start-ups with novel ideas are emerging. RA Capital Management and OrbiMed led the way in both total dollars invested and the number of venture capital funding rounds led in the biotech industry last yearthe only two firms to make it onto both lists. WebWith a total of USD 9.2bn, the oncology sector received the highest funding volume, followed by central nervous system (USD 6.0bn) and infectious diseases (USD 2.2bn). The capital total is a staggering 46% increase from its last set of funds, closed in May 2021 at $1.3 billion. as thousands of venture capital firms turned their attention to breakthrough artificial intelligence, cancer-detection technology, mental health treatments, digital doctor visits, diagnostics and more. Research. Versant had a busy 2021: It was involved in five IPOs. Freelance Writers: How To Pitch Crunchbase News, Wiz Becomes $10B Cybersecurity Unicorn But Says New Money Wont Go To Israel Amid Turmoil Over Judicial Reform, Tech Jobs: Here Are Dozens Of Artificial Intelligence Startups Hiring Now. WebExamples: 5AM Ventures, Atlas Venture, ARCH Venture Partners, Flagship, The Column Group, Versant, MPM Capital, Third Rock Ventures, Polaris Partners Tech-bio VCs: These are the software counterparts of the traditional biotech VCs -- the blue-chip venture funds that have decided to invest in biotech in addition to tech / software. Khosla Ventures bears the interests of Vinods passion for mentoring founders and entrepreneurs. The lead investor often acts as the liaison between the startups founder(s) and the other participating investors, or is implicitly trusted by other investors to find the best terms for everyone. Largest investment: 16.2 million shares of Theseus Pharmaceuticals worth $259 million at the time of its IPO, Total holding value of 2021 IPOs: $988.4 million. Although the two firms emerged as leaders in the data, they still make up a small part of the more than $120 billion in venture capital funds globally that poured into health and biotech startups as of Dec. 1 this year, Crunchbase data shows. Biotech companies are valued at $2T, a 4.1x increase since 2017. Fierce Pharma. See: http://www.sec.gov/Archives/edgar/data/1612343/000161234314000001/xslFormDX01/primary_doc.xml The firm seeks to invest in the software as a services (SaaS), cloud, data science, and artificial intelligence sectors. Octopus Ventures is a London and New York based venture capital firm, focused on backing unusually talented entrepreneurs. Essex Woodlands Health Ventures, City (cities) where offices are located: Palo Alto, CA; Houston; New York; London; Shanghai, Fund size and status: More than $2.5 billion under management across eight funds (4), Current fund: $900 million Fund VIII, closed 2009 (4), Current biopharma portfolio companies: Acura Pharmaceuticals, Biotoscana, Bioventus, Catalyst Biosciences, Chroma Therapeutics, Corium, Curis, Echo Therapeutics, Elusys Therapeutics, Horizon Pharma, IntegenX, LightSciences Oncology, Medicinova, Molecular Partners, Open Monoclonal Technology, Oraya Therapeutics, Revance Therapeutics, Symphogen, Ziopharm Oncology, City (cities) where offices are located: Cambridge, MA; New York; Palo Alto, CA, Fund size and status: $2.6 billion under management across seven funds, Current funds: $450 million Venrock VII, closed July 2014 and intended to invest in technology and healthcare companies; $350 million Venrock VI, closed 2010 (5), Current biopharma portfolio companies: Acceleron Pharma, Achaogen, Anacor Pharmaceuticals, Ariosa Diagnostics, Avalanche Biotech, AVEO Pharmaceuticals, Celladon, Cerulean, Constellation Pharmaceuticals, CymaBay Therapeutics, Fate Therapeutics, Hua Medicine, Infinity Pharmaceuticals, Intarcia Therapeutics, Ironwood Pharma, Juno Therapeutics, QuatRx Pharmaceuticals, Receptos, Vitae Pharmaceuticals, City (cities) where offices are located: Boston (6); South San Francisco, CA; Gainesville, FL; Munich, Fund size and status: More than $2.6 billion committed capital under management across five funds, Current fund: Approximately $300 million MPM BioVentures V L.P., closed 2010 (7), Current biopharma portfolio companies: 23andMe, Amphivena Therapeutics, Anthera Pharmaceuticals, Aratana Therapeutics, Astute Medical, Celladon, Cerecor, Chiasma, Conatus Pharmaceuticals, Epizyme, Iconic Therapeutics, Mitokyne, Proteon Therapeutics, Radius Health, Rhythm Pharmaceuticals, SAI, Selexys Pharmaceuticals, Sideris Pharmaceuticals, Solasia Pharma, Syndax Pharmaceuticals, Theraclone Sciences, True North Therapeutics, Vascular Pharmaceuticals, Verastem, City (cities) where offices are located: Princeton, NJ, and San Diego, Fund size and status: More than $2.7 billion under management across eight funds, Current fund: $500 million Domain Partners VIII, closed 2009, Current biopharma portfolio companies: Achaogen, Achillion Pharmaceuticals, Adynxx, Afferent Pharmaceuticals, Aldeyra Therapeutics, Alimera Sciences, Applied Proteomics, Ariosa Diagnostics, Ascenta Therapeutics, Asmacure, Astute Medical, Atara Biotherapeutics, aTyr Pharma, BioNano Genomics, Cantex Pharmaceuticals, Celator Pharmaceuticals, Clovis Oncology, CoDa Therapeutics, CoLucid Pharmaceuticals, Dicerna Pharmaceuticals, Domain Elite Holdings, Domain Russia Investments, Eddingpharm International Holdings, Epic Sciences, Esperion Therapeutics, Evoke Pharma, Five Prime Therapeutics, IntegenX, Marinus Pharmaceuticals, Meritage Pharma, NovaDigm Therapeutics, Ocera Therapeutics, Oraya Therapeutics, Orexigen Therapeutics, Otonomy, ProteinSimple, Regardo Biosciences, Sera Prognostics, Syndax Pharmaceuticals, Tobira Therapeutics, Tragara Pharmaceuticals, VentiRx Pharmaceuticals, Veracyte, Zogenix, Fund size and status: $2.8 billion under management across 10 funds, Current fund: $650 million InterWest Partners X, closed 2008, Current biopharma portfolio companies: Applied Genetic Technologies (AGTC), Alvine Pharmaceuticals, Arcion Therapeutics, Carbylan Therapeutics, Cebix, Centrexion, Cidara Therapeutics, Drais Pharmaceuticals, Eiger BioPharmaceuticals, Lycera, MacroGenics, Ocera Therapeutics, On Demand Therapeutics, Paratek Pharmaceuticals, PMV Pharma, QuatRx Pharmaceuticals, RadioRx, Tesaro, Trius Therapeutics, USDS, Xenon Pharmaceuticals, City (cities) where offices are located: Cambridge, MA. 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