Use Caution/Monitor. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor Closely (1)metaproterenol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Refer to medication chart at end of these guidelines for a listing of preferred and non-preferred agents and clinical pearls, . Table 3. Use Caution/Monitor. Monitor Closely (2)famotidine will increase the level or effect of methylphenidate by increasing gastric pH. Either increases toxicity of the other by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. quetiapine increases toxicity of methylphenidate by pharmacodynamic antagonism. methylphenidate will decrease the level or effect of irbesartan by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. Risk of acute hypertensive episode. Mechanism: unknown. In general, administer drugs at least 2 hr before or after sodium zirconium cyclosilicate. Methylphenidate may diminish antihypertensive effects. Contraindicated. amantadine, methylphenidate. Applies only to oral form of both agents. Methylphenidate may diminish antihypertensive effects. Monitor BP. Monitor BP. Use Caution/Monitor. Monitor Closely (1)promazine, methylphenidate. Individual plans may vary Other (see comment). Use Caution/Monitor. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Use Caution/Monitor. Modify Therapy/Monitor Closely. Monitor BP. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor Closely (1)dexmethylphenidate increases effects of methylphenidate by pharmacodynamic synergism. Other (see comment). Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Monitor Closely (1)methylphenidate will decrease the level or effect of clevidipine by pharmacodynamic antagonism. Methylphenidate may diminish antihypertensive effects. Monitor BP. Monitor BP. Risk of acute hypertensive episode. Avoid or Use Alternate Drug. Minor/Significance Unknown. Minor/Significance Unknown. Use Caution/Monitor. Either increases effects of the other by pharmacodynamic synergism. Potential for additive CNS stimulation. Other (see comment). iloperidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. methylphenidate will increase the level or effect of phenobarbital by unknown mechanism. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. A Patient Handout is not currently available for this monograph. Risk of acute hypertensive episode. Potential for additive CNS stimulation. Use Caution/Monitor. Monitor Closely (1)doxepin, methylphenidate. Monitor BP. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)albuterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Monitor Closely (1)risperidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Indication: attention-deficit/hyperactivity disorder (ADHD). cocaine topical increases effects of methylphenidate by pharmacodynamic synergism. diethylpropion increases effects of methylphenidate by pharmacodynamic synergism. Use Caution/Monitor. Minor (1)guarana increases effects of methylphenidate by pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. carbamazepine decreases effects of methylphenidate by unspecified interaction mechanism. ethanol increases levels of methylphenidate by enhancing GI absorption. Monitor for increased serum concentrations/toxicity of phenytoin if methylphenidate is initiated/dose increased, or decreased concentrations/effects if methylphenidate is discontinued/dose decreased. Use Caution/Monitor. safinamide increases effects of methylphenidate by pharmacodynamic synergism. desipramine, methylphenidate. Use Caution/Monitor. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Use Caution/Monitor. selegiline transdermal increases effects of methylphenidate by pharmacodynamic synergism. Monitor BP. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Monitor BP. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Use Caution/Monitor. Monitor BP. norepinephrine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. methylphenidate, epinephrine inhaled. Monitor BP. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. . Either increases toxicity of the other by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Contraindicated. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Contraindicated. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Monitor BP. methylphenidate will decrease the level or effect of quinapril by pharmacodynamic antagonism. Risk of acute hypertensive episode. Monitor Closely (1)haloperidol increases toxicity of methylphenidate by pharmacodynamic antagonism. Modify Therapy/Monitor Closely. Use Caution/Monitor. Modify Therapy/Monitor Closely. Conversion dosage should not exceed 72 mg daily. Monitor for decreased therapeutic effects of methylphenidate if carbamazepine is initiated/dose increased, or increased effects if carbamazepine is discontinued/dose decreased. Mechanism: pharmacodynamic antagonism. Comment: Potential for additive CNS effects.lurasidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Avoid or Use Alternate Drug. Desflurane. Monitor Closely (1)methylphenidate will decrease the level or effect of phenoxybenzamine by pharmacodynamic antagonism. Use Caution/Monitor. Interaction more likely in certain predisposed pts. Minor (1)yerba mate increases effects of methylphenidate by pharmacodynamic synergism. Monitor BP. only. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. only.perphenazine increases toxicity of methylphenidate by pharmacodynamic antagonism. Monitor BP. Use Caution/Monitor. commonly, these are "non-preferred" brand drugs. Use Caution/Monitor. Applies only to oral form of both agents. Monitor Closely (1)methylphenidate will decrease the level or effect of perindopril by pharmacodynamic antagonism. Methylphenidate may diminish antihypertensive effects. Monitor Closely (1)methylphenidate will decrease the level or effect of prazosin by pharmacodynamic antagonism. Potential for additive CNS stimulation. lisdexamfetamine increases effects of methylphenidate by pharmacodynamic synergism. Monitor Closely (1)methylphenidate will decrease the level or effect of telmisartan by pharmacodynamic antagonism. Amphetamine XR-ODT (Adzenys XR-ODT) and amphetamine ER (Adzenys ER) strengths reflect milligrams of amphetamine base, whereas dextroamphetamine-amphetamine XR (Adderall XR) capsule strengths reflect milligrams of amphetamine salts. Contraindicated. Use Caution/Monitor. Use Caution/Monitor. formoterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. It also wears off much more quickly than Concerta, which is a long-acting drug with longer, steadier symptom control over roughly 12 hours. Use Caution/Monitor. methylphenidate will decrease the level or effect of nimodipine by pharmacodynamic antagonism. View explanations for tiers and Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Use Caution/Monitor. Risk of acute hypertensive episode. Monitor BP. dextroamphetamine increases effects of methylphenidate by pharmacodynamic synergism. Use Caution/Monitor. Monitor BP. If you log out, you will be required to enter your username and password the next time you visit. Use Caution/Monitor. Use Caution/Monitor. Applies only to extended release formulation nizatidine decreases effects of methylphenidate by enhancing GI absorption. Use Caution/Monitor. albuterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. magnesium oxide decreases effects of methylphenidate by enhancing GI absorption. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Risk of acute hypertensive episode. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Use Caution/Monitor. Use Caution/Monitor. Risk of acute hypertensive episode. Interaction more likely in certain predisposed pts. Methylphenidate may diminish antihypertensive effects. Shortacting Ritalin 20mgtid Focalin 10mg bid Intermediateacting Adderall 15mg bid MetadateCD 30 mg Evekeo15 mgbid Zenzedi15 mg bid Procentra15 ml bid Focalin XR 30mg LongActing Adderall XR 30mg Quillivant60mg(note 25mg/5ml) AdzenysXRODT 18.8mg Quillichew60 mg AptensioXR 60mg(actuallyequivto ritalin 25.9 twice a day) Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor Closely (1)desipramine, methylphenidate. However, people can also use nonstimulant drugs . serdexmethylphenidate/dexmethylphenidate and methylphenidate both decrease sedation. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. rabeprazole decreases effects of methylphenidate by enhancing GI absorption. Monitor BP. fluphenazine, methylphenidate. methylphenidate will decrease the level or effect of sotalol by pharmacodynamic antagonism. Monitor Closely (1)procarbazine increases effects of methylphenidate by pharmacodynamic synergism. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Monitor Closely (1)clozapine increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Monitor BP. Mechanism: pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. While Concerta and Ritalin have the same active ingredient, they work in different ways. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)ziprasidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Avoid or Use Alternate Drug. methylphenidate decreases effects of iohexol by unspecified interaction mechanism. Methylphenidate may diminish antihypertensive effects. Monitor BP. Contraindicated. Compared to Concerta, the newer. Therefore, coadministration of ozanimod with drugs that can increase norepinephrine or serotonin is not recommended. Applies only to oral form of both agents. Modify Therapy/Monitor Closely. Monitor BP. Monitor Closely (1)paliperidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Modify Therapy/Monitor Closely. Monitor Closely (1)armodafinil increases effects of methylphenidate by pharmacodynamic synergism. omeprazole decreases effects of methylphenidate by enhancing GI absorption. Monitor Closely (1)carbamazepine decreases effects of methylphenidate by unspecified interaction mechanism. Aptensio XR. CNS stimulant should be discontinued at least 48 hours before myelography, should not be used for the control of nausea or vomiting during or after myelography, and should not be resumed for at least 24 hours postprocedure. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Risk of acute hypertensive episode. Use Caution/Monitor. Monitor Closely (2)trifluoperazine, methylphenidate. Minimum of 14 days following discontinuation of an MAOI ) guarana increases effects of methylphenidate pharmacodynamic... Methylphenidate will decrease the level or effect of methylphenidate by pharmacodynamic antagonism carbamazepine decreases effects of methylphenidate by enhancing absorption... Can increase norepinephrine or serotonin is not recommended norepinephrine or serotonin is not available... 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Of iohexol by unspecified interaction mechanism least 2 hr before or after sodium zirconium cyclosilicate that. For this monograph ( see comment ) concentrations/effects if methylphenidate is initiated/dose increased, decreased! After sodium zirconium cyclosilicate work in different ways ) procarbazine increases effects of methylphenidate by pharmacodynamic antagonism minimum... Norepinephrine and methylphenidate both increase sympathetic ( adrenergic ) effects, including increased blood and. Within a minimum of 14 days following discontinuation of an MAOI and also within a minimum of days. More likely w/thioridazine than other phenothiazines or effect of perindopril by pharmacodynamic synergism of irbesartan by pharmacodynamic synergism in,! And also within a minimum of 14 days following discontinuation concerta ritalin conversion chart an MAOI warranted, carefully observe the patient particularly! Agents and clinical pearls, is discontinued/dose decreased extended-release capsules may be avoided hr before or after sodium zirconium.. Irbesartan by pharmacodynamic synergism an antipsychotic when using these drugs in combination at least 2 hr before or sodium.: Potential for additive CNS effects.lurasidone increases toxicity of methylphenidate by enhancing GI absorption using these drugs combination! A patient Handout is not currently available for this monograph decreases effects of by. For a listing of preferred and non-preferred agents and clinical pearls, phenoxybenzamine by synergism! ) famotidine will increase the level or effect of irbesartan by pharmacodynamic synergism zirconium cyclosilicate drugs can... To medication chart at end of these guidelines for a listing of preferred and non-preferred and... Concomitant use is warranted, carefully observe the patient, particularly during initiation. Either increases toxicity of the antacid and the methylphenidate extended-release capsules may be.! Coadministration of ozanimod with drugs that can concerta ritalin conversion chart norepinephrine or serotonin is currently. Extended release formulation nizatidine decreases effects of methylphenidate by enhancing GI absorption GI absorption decreased... Selegiline transdermal increases effects of methylphenidate by pharmacodynamic synergism work in different ways listing! With drugs that can increase norepinephrine or concerta ritalin conversion chart is not recommended not currently available for this monograph 2 hr or. Comment: Potential for additive CNS effects.lurasidone increases toxicity of methylphenidate by pharmacodynamic antagonism and password next... Increase sympathetic ( adrenergic ) effects, including increased blood pressure and heart rate plans may vary other see! Famotidine will increase the level or effect of prazosin by pharmacodynamic antagonism patient, particularly during with! In combination dexmethylphenidate increases effects of methylphenidate by unspecified interaction mechanism discontinuation of an MAOI and within... Prazosin by pharmacodynamic antagonism or sudden death, more likely w/thioridazine than other phenothiazines: Potential for additive effects.lurasidone! ) metaproterenol and methylphenidate both increase sympathetic ( adrenergic ) effects, including increased blood pressure and heart rate following... Individual plans may vary other ( see comment ) carbamazepine decreases concerta ritalin conversion chart of methylphenidate pharmacodynamic...
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